From acute Q fever to endocarditis: serological follow-up strategy.
نویسندگان
چکیده
The serological evolution from acute Q fever to endocarditis is reported for 22 patients, with a median lag time of 3 months. From this data, we propose a follow-up strategy of serological testing at the third and sixth months after acute Q fever to obtain an early diagnosis of chronic infection.
منابع مشابه
Serological differentiation between acute (late control) and endocarditis Q fever.
AIMS To differentiate the serological profiles of chronic (endocarditis) Q fever from the late follow up of acute cases. METHODS Twenty patients (10 diagnosed with acute and 10 with endocarditis Q fever) were studied. Those diagnosed with acute infection were followed up from 2.5 to 88 months (mean 35.8 months). Serological variables included indirect immunofluorescence against phase I and II...
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PURPOSE In 2007, a large goat-farming-associated Q fever outbreak occurred in the Netherlands. Data on the clinical outcome of Dutch Q fever patients are lacking. The current advocated follow-up strategy includes serological follow-up to detect evolution to chronic disease and cardiac screening at baseline to identify and prophylactically treat Q fever patients in case of valvulopathy. However,...
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To the Editor—We read with interest the recent paper on Q fever by Healy et al [1], which describes the results of initial and follow-up serologic analysis after an outbreak of Q fever, and the discrepancy in test results obtained from different reference laboratories. This article raises the problem of management of asymptomatic patients with a chronic serological profile (phase 1 serum level ...
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BACKGROUND Serological follow-up of acute Q-fever patients is important for detection of chronic infection but there is no consensus on its frequency and duration. The 2007-2009 Q-fever epidemic in the Netherlands allowed for long-term follow-up of a large cohort of acute Q-fever patients. The aim of this study was to validate the current follow-up strategy targeted to identify patients with ch...
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BACKGROUND During the Dutch Q fever epidemic more than 4,000 Q fever cases were notified. This provided logistical challenges for the organisation of serological follow-up, which is considered mandatory for early detection of chronic infection. The aim of this study was to investigate the proportion of acute Q fever patients that received serological follow-up, and to identify regional differen...
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عنوان ژورنال:
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
دوره 44 10 شماره
صفحات -
تاریخ انتشار 2007